Anemia in CKD


What is anemia?

Anemia is a condition in which you lack enough healthy red blood cells to carry adequate oxygen to your body’s tissues. Having anemia, also referred to as low hemoglobin, can make you feel tired and weak.

There are many forms of anemia, each with its own cause. Anemia can be temporary or long-term and can range from mild to severe. In most cases, anemia has more than one cause. See your doctor if you suspect that you have anemia. It can be a warning sign of serious illness.

Treatments for anemia, which depend on the cause, range from taking supplements to having medical procedures. You might be able to prevent some types of anemia by eating a healthy, varied diet.

The types of anemia:

Aplastic anemia:

a condition that occurs when your body stops producing enough new blood cells. The condition leaves you fatigued and more prone to infections and uncontrolled bleeding. A rare and serious condition, aplastic anemia can develop at any age. It can occur suddenly, or it can come on slowly and worsen over time. It can be mild or severe. Treatment for aplastic anemia might include medications, blood transfusions or a stem cell transplant, also known as a bone marrow transplant.

Iron deficiency anemia:

Iron deficiency anemia is a common type of anemia — a condition in which blood lacks adequate healthy red blood cells. Red blood cells carry oxygen to the body’s tissues. As the name implies, iron deficiency anemia is due to insufficient iron. Without enough iron, your body can’t produce enough of a substance in red blood cells that enables them to carry oxygen (hemoglobin). As a result, iron deficiency anemia may leave you tired and short of breath. You can usually correct iron deficiency anemia with iron supplementation. Sometimes additional tests or treatments for iron deficiency anemia are necessary, especially if your doctor suspects that you’re bleeding internally.

Sickle cell anemia:

Sickle cell anemia is one of a group of inherited disorders known as sickle cell disease. It affects the shape of red blood cells, which carry oxygen to all parts of the body. Red blood cells are usually round and flexible, so they move easily through blood vessels. In sickle cell anemia, some red blood cells are shaped like sickles or crescent moons. These sickle cells also become rigid and sticky, which can slow or block blood flow.

Thalassemia:

Thalassemia is an inherited blood disorder that causes your body to have lowered levels of hemoglobin than normal. Hemoglobin enables red blood cells to carry oxygen. Thalassemia can cause anemia, leaving you fatigued.

Vitamin deficiency anemia:

Vitamin deficiency anemia is a lack of healthy red blood cells caused by lower-than-usual amounts of vitamin B-12 and folate. This can be caused by a lack of food containing vitamin B-12 and folate, or if your body has trouble absorbing or processing these vitamins. Without these nutrients, the body produces red blood cells that are too large and don’t work properly. This reduces their ability to carry oxygen.

How is anemia related to chronic kidney disease?

Anemia is a common complication of chronic kidney disease (CKD). CKD means your kidneys are damaged and can’t filter blood the way they should. This damage can cause wastes and fluid to build up in your body. CKD can also cause other health problems. Anemia is less common in early kidney disease, and it often gets worse as kidney disease progresses and more kidney function is lost.