The G401 cell line is a human renal cell carcinoma (RCC) cell line derived from a primary tumor in a 2-year-old Caucasian female with Wilms’ tumor. Wilms’ tumor is a pediatric malignancy that arises from the developing kidneys and is the most common type of kidney cancer in children. The G401 cell line is widely…
The Renca cell line is a murine (mouse) renal cell adenocarcinoma cell line that originated from a spontaneous tumor in a BALB/c mouse. This cell line is widely used as a preclinical in vitro and in vivo model for studying the biology of renal cell carcinoma and for evaluating potential therapeutic strategies for this type…
The HEK-293 cell line (Human Embryonic Kidney 293 cells) is a widely used, well-established cell line in biomedical research. It was derived from human embryonic kidney cells grown in tissue culture and transformed with sheared adenovirus 5 DNA. This transformation event led to the incorporation of a portion of the adenoviral genome into the cells,…
The Caki-1 cell line is a human renal cell carcinoma (RCC) cell line derived from a metastatic site (skin) of a clear cell renal carcinoma in a 49-year-old Caucasian male. This cell line is widely used as an in vitro model for studying the biology of renal cell carcinoma and for evaluating potential therapeutic strategies…
The 786-O cell line is a human renal cell carcinoma (RCC) cell line. It was established from the primary tumor of a 58-year-old Caucasian male with clear cell renal carcinoma. The 786-O cell line is commonly used in cancer research to study the biology of renal cell carcinoma and to investigate potential therapeutic strategies for…
The A498 cell line is a human cancer cell line derived from a patient with renal cell carcinoma (RCC), which is a type of kidney cancer. The A498 cell line is widely used in cancer research, particularly in studying the biology of renal cell carcinoma, drug resistance, and the development of novel therapeutics. Researchers use…
Overview: Kidney stones (also called renal calculi, nephrolithiasis, or urolithiasis) are hard deposits made of minerals and salts that form inside your kidneys. Diet, excess body weight, some medical conditions, and certain supplements and medications are among the many causes of kidney stones. Kidney stones can affect any part of your urinary tract — from…
What is anemia? Anemia is a condition in which you lack enough healthy red blood cells to carry adequate oxygen to your body’s tissues. Having anemia, also referred to as low hemoglobin, can make you feel tired and weak. There are many forms of anemia, each with its own cause. Anemia can be temporary or…
The average human adult has more than 5 liters (6 quarts) of blood in his or her body. Blood carries oxygen and nutrients to living cells and takes away their waste products. It also delivers immune cells to fight infections and contains platelets that can form a plug in a damaged blood vessel to prevent…
Early kidney disease usually doesn’t have any symptoms. Testing is the only way to know how well your kidneys are working. People who have diabetes, high blood pressure, heart disease, or a family history of kidney failure are more exposed to chronic kidney disease and should get tested more often. The sooner chronic kidney disease…
